The alteration of stress-related physiological parameters after probiotics administration in oral surgeons with different degrees of surgical experience

doi: 10.7417/CT.2020.2214

  • A. Pacifici Department of Oral and Maxillofacial Sciences, Sapienza University of Rome
  • L. Pacifici Department of Oral and Maxillofacial Sciences, Sapienza University of Rome
  • M. Nuzzolese Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari
  • G. Cascella Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari
  • A. Ballini Department of Biosciences, Biotechnologies and Biopharmaceutics, Campus Universitario “Ernesto Quagliariello”, University of Bari “Aldo Moro”, Bari - Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples - Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
  • L. Santacroce Ionian Department, University of Bari “Aldo Moro”, Bari; School of Technical Medical Sciences, “A. Xhuvani” University, Elbasan, Albania
  • G. Dipalma Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari
  • E. Aiello Tecnologica Research Institute, Marrelli Health, Crotone
  • M. Amantea Tecnologica Research Institute, Marrelli Health, Crotone
  • R. Saini Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari
  • S. Cantore Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari - Sorriso & Benessere Ricerca e Clinica S.r.l., Bari, Italy
  • F. Inchingolo Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari
  • S. Scacco Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy

Abstract

Purpose
Stress is a multifactorial and complex pathway, gaining growing attention from the healthcare community. Surgeons are subjected to higher levels of stress, due to surgical procedures that are demanding and repetitive; unfortunately, high-stress levels may also cause side-effects, as surgical mistakes. This study aimed to evaluate the efficacy of specific probiotics strains formula on stress levels in oral and maxillofacial surgeons, to improve their quality of life.


Methods
We have investigated the hormonal (salivary Cortisol; sC), immune (salivary Immunoglobulin A; sIgA) and cardiovascular (Heart rate, HR, and systolic blood pressure, SBP) responses induced by stress conditions in 40 oral surgeons, randomly selected and allocated, according to their experience level, in three categories: senior, expert, and junior.


Results
The results described how the number of heartbeats/ minute and SBP are slightly raised in all surgeons at different timepoints. Such data allow us to assess that work-related stress can induce an increase in cardiovascular parameters, even if they are not significantly modified by the use of probiotics. On the other hand, our data indicate that 10 weeks of probiotic integration may induce the improvement of other stress-related physiological parameters in oral surgeons with different degrees of surgical experience, such as the salivary cortisol levels, even under stress conditions. Moreover, in the test group (probiotics administration), the immunoglobulin levels were higher than the control (placebo administration) group: this happens as a consequence of the regular use of probiotics, which may induce an increased number of IgA producing cells.


Conclusions
Our data indicated that 10 weeks of probiotics-enriched diet modify some stress-related physiological parameters in oral surgeons with different degrees of surgical experience, but it does not impact on the overall cardiovascular risk.

Published
2020-04-22
How to Cite
PACIFICI, A. et al. The alteration of stress-related physiological parameters after probiotics administration in oral surgeons with different degrees of surgical experience. La Clinica Terapeutica, [S.l.], v. 171, n. 3, p. e197 - e208, apr. 2020. ISSN 1972-6007. Available at: <http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/643>. Date accessed: 27 may 2020.
Section
Clinical Trial