Personalized medicine in psychiatric disorders: prevention and bioethical questions

doi: 10.7417/CT.2019.2169

  • A. Quattrocchi Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
  • Z. Del Fante Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
  • N. Di Fazio Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
  • S. Romano Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
  • G. Volonnino Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
  • V. Fazio Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
  • P. Santoro Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy

Abstract

La medicina personalizzata rappresenta un emergente approccio alla medicina, che mira ad applicare l’attuale conoscenza scientifica nello studio della suscettibilità individuale allo sviluppo di determinate patologie al fine di prevenirne l’insorgenza e identificare la risposta ad un trattamento farmacologico. Lo scopo del presente studio è quello di analizzare le implicazioni etiche dell’applicazione di tale approccio nella prevenzione delle malattie psichiatriche, attraverso lo studio di specifiche variazioni genetiche e modificazioni epigenetiche. Tuttavia, dallo studio del genoma umano attraverso specifiche tecnologie scientifiche originano numerose domande di natura bioetica.


 


Abstract


Personalized medicine is an emerging approach to medicine that applies scientific knowledge to predict individual susceptibility to certain pathologies and to identify their response to pharmacological treatments. The aim of the study is to analyze the ethical implications of the use of personalized medicine in the prevention of psychiatric disorders, through the study of specific genetic variations and epigenetic modifications. However, the use of technologies aimed at studying the human genome, in order to prevent these pathologies, cause many bioethical questions.

Published
2019-11-06
How to Cite
QUATTROCCHI, A. et al. Personalized medicine in psychiatric disorders: prevention and bioethical questions. La Clinica Terapeutica, [S.l.], v. 170, n. 6, p. e421 - e424, nov. 2019. ISSN 1972-6007. Available at: <http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/519>. Date accessed: 15 nov. 2019.