Late-onset non-familial acrokeratosis verruciformis of Hopf: a case report

doi: 10.7417/CT.2019.2168

  • V. Faina Department of Dermatology, Policlinico Umberto I, “Sapienza” University of Rome, Italy
  • F. Magri Department of Dermatology, Policlinico Umberto I, “Sapienza” University of Rome, Ital
  • A. Sernicola Department of Dermatology, Policlinico Umberto I, “Sapienza” University of Rome, Italy
  • C. Chello Department of Dermatology, Policlinico Umberto I, “Sapienza” University of Rome, Italy
  • N. Gagliostro Department of Dermatology, Policlinico Umberto I, “Sapienza” University of Rome, Italy
  • T. Grieco Department of Dermatology, Policlinico Umberto I, “Sapienza” University of Rome, Italy

Abstract

Acrokeratosis verruciformis of Hopf is a rare heritable autosomal dominant genodermatosis and keratinization disorder, first described in 1931 by Hopf. It presents with multiple flat skin colored papules, mainly localized at the dorsal region of the hands and feet. AKV is an allelic disorder, associated with heterozygous missense mutation in ATP2A2 gene, which is involved in Darier’s disease. Usually, it arises in early life but rare sporadic cases with adult onset have been reported. We report a case of late-onset non-familial AKV in a 52-year old patient

Published
2019-11-06
How to Cite
FAINA, V. et al. Late-onset non-familial acrokeratosis verruciformis of Hopf: a case report. La Clinica Terapeutica, [S.l.], v. 170, n. 6, p. e418 - e420, nov. 2019. ISSN 1972-6007. Available at: <http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/518>. Date accessed: 15 nov. 2019.