Anisometropia and isoametropia associated with microstrabismus: effectiveness of late anti-amblyopia treatment

doi: 10.7417/CT.2019.2158

  • R. Migliorini Department of Sense Organs, University of Rome “Sapienza”, Rome, Italy
  • A. M. Comberiati Department of Sense Organs, University of Rome “Sapienza”, Rome, Italy
  • F. Pacella Department of Sense Organs, University of Rome “Sapienza”, Rome, Italy
  • R. Monsellato Department of Sense Organs, University of Rome “Sapienza”, Rome, Italy
  • L. Arrico Department of Sense Organs, University of Rome “Sapienza”, Rome, Italy

Abstract

Purpose
Outcomes Research Study on patients suffering from anisometropia or isoametropia associated with amblyopia and microstrabismus to show the impact of late occlusion treatment on therapeutic prognosis.


Materials and methods
Enrollment of all the eligible patients presenting to recruiting centers at the Department of  Pediatric Ophthalmology and Strabismus - Ophthalmological Clinic - Policlinico Umberto I - Rome. At baseline, all patients will undergo an opthalmologic evaluation. Recruited patients will be followed for a 2-year period.
Our test group was composed of 31 patients, 11 with bilateral and 20 with monolateral amblyopia, totalling  42 amblyopic eyes, and it was assessed – always by the same examiner – with the help of the following orthoptic examinations: Wirt test, Irvine-Jampolsky test (4 dioptre fixation task), Visuscope, Cover Test, Bagolini striated glasses, and Worth lights test. We assessed pre-post treatment variations observed in the overall group of amblyopic eyes, regardless of the differences between RE and LE.


Outcomes
Of the 31 children, 58.1% were males and 41.9% female, average age between 6 and 14 years. Of the 42 amblyopic eyes, after daily occlusion of 8 hours ± 2.30 SD, we recorded an improvement of  71.4%, and visual acuity increased from an average of 0.4 LogMAR to 0.1 LogMAR.


Conclusion
Late anti-amblyopic occlusion treatment proved effective in the long term for children 6 to 12 years, specifically regarding visual acuity, fixation, stereopsis, and binocular collaboration in patients suffering from anisometropia or isoametropia and microstrabismus.

Published
2019-09-30
How to Cite
MIGLIORINI, R. et al. Anisometropia and isoametropia associated with microstrabismus: effectiveness of late anti-amblyopia treatment. La Clinica Terapeutica, [S.l.], v. 170, n. 5, p. e339 - e344, sep. 2019. ISSN 1972-6007. Available at: <http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/484>. Date accessed: 22 oct. 2019.