A characteristic type of retinal microvascular abnormalities in a patient with Neurofibromatosis type 1

doi: 10.7417/CT.2019.2101

  • A. Moramarco Department of Organ of Sense, Sapienza University of Rome, Rome
  • A. Lambiase Department of Organ of Sense, Sapienza University of Rome, Rome
  • F. Mallone Department of Organ of Sense, Sapienza University of Rome, Rome
  • E. Miraglia Department of Dermatology, Sapienza University of Rome, Rome, Italy
  • S. Giustini Department of Dermatology, Sapienza University of Rome, Rome, Italy

Abstract

This study aims to describe a typical retinal microvascular abnormality in patients with neurofibromatosis type 1 (NF-1).


A 64-year-old man with diagnosis of NF-1 was evaluated by complete ophthalmological examination, including fluorescein angiography and spectral Domain OCT in Near-Infrared (NIR-OCT) modality. Slit lamp exam showed the presence of more than 10 Lisch nodules for each eye. Ophthalmic examinations and NIR-OCT scans showed the presence of retinal tortuous vessels ending in a ‘puff of smoke’ arrangement. The clinical significance as diagnostic and prognostic factor of this novel type of retinal microvascular abnormality in NF-1 should be further investigated

Published
2019-02-14
How to Cite
MORAMARCO, A. et al. A characteristic type of retinal microvascular abnormalities in a patient with Neurofibromatosis type 1. La Clinica Terapeutica, [S.l.], v. 1, n. 170, p. e4 - e9, feb. 2019. ISSN 1972-6007. Available at: <http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/337>. Date accessed: 25 aug. 2019.