Abstract
Intradermal therapy (mesotherapy) is a technique used to inject drugs into the surface layer of the skin. The intradermal micro deposit allows to modulate the kinetics of drugs, slowing down its absorption and prolonging the local mechanism of action. This technique is applied in the treatment of some forms of localized pain when a systemic drug-saving effect is useful, when it is necessary to synergize with other pharmacological or non-pharmacological therapies, when other therapies have failed or cannot be used. Our study evaluated 62 patients with cervicobrachial pain. The Italian Society of Mesotherapy has recommended not to use drug mixtures in mesotherapy. The aim of the study was to retrospectively evaluate the use of drug mixtures, at different dosages and dilutions, by analyzing clinical data. We also wanted to verify if the weekly treatment algorithm is useful for managing the pain of patients with cervical pain. Our study suggests that low intradermal doses of the drug can induce a significant clinical response with 3.5 + 1.7 sessions on a weekly basis. Our study confirms that a lower dose could be better for inducing a significant clinical response. We invite researchers to pursue this line of research in other forms of localized pain.